结肠镜检查结直肠癌患者的临床特征改变研究

摘要

Objective To investigate the changes of clinical features of colorectal cancer patients by colonoscopy in re -cent 10 years.Methods Clinical data of 15692 patients were analyzed retrospectively .Results 1249 patients with colorectal cancer were detected(7.96%).The average age of a post Dukes stage in patients with colorectal cancer was higher than a former Dukes stage.The average ages of A stage and B stage were significantly lower than C 1 stage,C2 stage and D stage(all P <0.05). The sex ratio of men to women was 1.39∶1.Since 2010,the overall detection rate and detection rate for female patients increased slowly.The average age of all patients was (59.54 ±12.86).Since 2009,the average age of all patients increased slowly .Since 2010,the proportion of right colon cancer had slowly increased ,but the proportion of rectal cancer and left colon cancer had slowly decreased.Conclusion Colonoscopy is an important means for early diagnosis of colorectal cancer .The overall detection rate and detection rate for female patients increase slowly .Colorectal cancer has the aging trend with lesions shifting to right .%目的：探讨近10年结肠镜检查结直肠癌患者的临床特征变化。方法回顾性分析2004年1月至2013年12月行结肠镜检查的15692例受检者的临床资料。结果总共检查出1249例结直肠癌患者（7．96％）。从分期上看，结直肠癌患者的后一个 Dukes 分期的平均年龄均高于前一个分期的平均年龄，A 期与 B 期的平均年龄均显著低于 C1期、C2期、D 期的平均年龄（P 均＜0．05）。男女患者的性别比例为1．39∶1，从2010年起总体检出率和女性患者的检出率呈缓慢增长趋势。结直肠癌患者的平均年龄是（59．54±12．86）岁，从2009年起结直肠癌患者的平均年龄呈缓慢增长趋势。从2010年起右半结肠癌的比例缓慢增加，而直肠癌与左半结肠癌的比例缓慢下降。结论结肠镜是早期诊断结直肠癌的重要手段，结直肠癌的总体检出率及女性患者的检出率近年来均呈缓慢增长的趋势，且有老龄化和发病部位右移的趋势。