GC法测定复方帕吉林片中盐酸帕吉林的含量

摘要

Objective To establish a method for determination of pargyline in compound pargyline tablets. Methods The chromatographic column was DB-624(30 m ×0. 32 mm, 1.4 μm). The column temperature programming was 110 t maintained for 12 min before rising to 250 °C (at rate of 40 t/min) that was maintained for 10 min. For FID detection,the temperature was 300 °C. The split ratio was 20:1. Results The linear range of pargyline was within 0.21-1.05 mg/ml(Y =0.6949X -0.0112, r =0.9995). Conclusion This method to determinate pargyline is reliable and accurate.%目的 测定复方帕吉林片中盐酸帕吉林的含量.方法 改性聚乙二醇毛细管柱(30 m ×0.32 mm,1.4 μm),柱温110℃保持12 min,再以40℃/min的速度升温至250℃保持10 min；进样口温度为270℃；氢火焰检测器,检测器温度为300℃；分流比为20:1.结果 盐酸帕吉林的回归方程为:Y =0.6949X -0.0112,r=0.9995,表明盐酸帕吉林在0.21～1.05mg/ml的浓度范围内具有良好的线性关系.结论 本法测定复方帕吉林片中的盐酸帕吉林的含量准确可靠.