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RASAGILINE FOR PARKINSON'S DISEASE MITIGATION

机译:雷帕吉林治疗帕金森氏病

摘要

PROBLEM TO BE SOLVED: To provide a method for identifying, and reducing the rate of progression of, Parkinson's disease in an early stage Parkinson's disease patient.SOLUTION: There is provided a method for mitigating Parkinson's disease by periodically administering a pharmaceutical composition comprising a therapeutically effective amount of rasagiline[(R)-2,3-dihydro-N-(2-propynyl)-1H-inden] or a pharmaceutically acceptable salt of rasagiline to a patient, thereby mitigating the disease. The method includes: reducing the rate of progression; delaying the need for anti-Parkinsonian therapy; reducing the risk of a Parkinson's disease patient requiring symptomatic anti-Parkinsonian therapy; and reducing the functional decline.
机译:要解决的问题:提供一种在帕金森氏病早期患者中鉴定和降低帕金森氏病进展的方法。解决方案:提供了一种通过定期施用包含治疗剂的药物组合物减轻帕金森氏病的方法。雷沙吉兰[R,-2,3-二氢-N-(2-丙炔基)-1H-茚满]或药学上可接受的雷沙吉兰盐对患者的有效量,从而减轻了疾病。该方法包括:降低进展速度;延迟了抗帕金森病治疗的需求;减少需要对症帕金森病对症治疗的帕金森氏病患者的风险;并减少功能下降。

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