无抽搐电休克治疗中麻醉药物应用的研究进展

摘要

无抽搐电休克治疗(MECT)在精神科较为常用,与传统的电休克治疗相比,MECT在治疗前给患者施用一定量的肌肉松弛剂和静脉麻醉药,更利于减轻患者在治疗中的紧张情绪和身体损伤.丙泊酚和琥珀胆碱是目前MECT最常用的麻醉药物,然而由于丙泊酚对循环系统和神经系统的影响,以及琥珀胆碱特殊的药理作用,丙泊酚和琥珀胆碱药在MECT中的应用受到不少争议.另外,通电治疗也可能带来一些并发症.麻醉药物应用的更新、优化和合理搭配成为目前迫切需要解决的问题.%Modified electroconvulsive therapy(MECT) is a common psychiatric treatment.Compared with conventional electroconvulsive therapy ,a certain amount of muscle relaxants and intravenous anesthetics are administered to the patient before treatment,which is more conducive to reducing the tension during the treatment.At present,the most commonly used anesthetic drugs in MECT are propofol and succinylcholine.However,due to the effects of propofol on the circulatory system and nervous system, and the special pharmacological effects of succinylcholine , the application of these two drugs has received a lot of controversies in the use of MECT.In addition,electricity treatment may also bring about some complica-tions.The renewal,optimization and reasonable matching of anesthetic drug applications have become an urgent problem in the field.