感染性休克患者血乳酸清除率与APACHEⅡ评分相关性分析

摘要

目的 研究感染性休克患者血乳酸清除率与APACHEⅡ评分的相关性.方法 对95例感染性休克患者入住重症监护病房6 h内进行动脉血乳酸浓度测定,根据APACHEⅡ评分分为两组:APACHEⅡ评分≥20分为A组,＜20分为B组;根据患者治疗结果,将患者分为存活组和死亡组.观察血乳酸清除率与患者病死率和APACHEⅡ评分的相关性.结果 A组患者血乳酸清除率明显高于B组(P＜0.01),病死率明显低于B组患者;死亡组患者血乳酸清除率明显低于存活组患者(P＜0.01);存活组及死亡组患者血乳酸清除率与APACHEⅡ评分均呈显著负相关性(P＜0.05).结论 乳酸清除率是判断感染性休克患者病情严重程度和预后的早期、敏感指标.%Objective To explore the correlation between lactate clearance rate and APACHE II scores in patients with septic shock. Methods The measurement of arterial blood lactic acid concentration was made in 95 patients with septic shock within 6 h when they were admitted in the intensive care unit. They were divided into group A( APACHE II score ≥20 )and group B( APACHE II score < 20 ) according to the APACHE II scores. They also were divided into survival group and death group according to their therapeutic results. Observation was made in the correlation between blood lactate clearance rate, mortality rate and APACHE II scores. Results The blood lactate clearance rate of group A was significantly higher, and the mortality rate was significantly lower than that of group B( P < 0.05 ). The lactate clearance rate of the death group was significantly lower than that of the survival group( P < 0. 01 ). There was a negative correlation between the lactate clearance rate and the APACHEII scores in both death group and survival group( P < 0.01 ). Conclusion Lactate clearance rate is an early sensitive index indicating the severity of illness in patients with septic shock.