62例习惯性流产女性血清同型半胱氨酸、叶酸、孕酮检测结果分析

摘要

Objective:To investigate the relationship between serum homocysteine,folic acid,progesterone and habitual abortion. Method:The case-control study method was used,62 women with non pregnant who at least 2 times continuous natural abortion history were selected as the habits abortion group,at the same time 62 pregnant women in the hospital for health examination were selected as the reference group,the homocysteine,progesterone and folic acid detection results were observed and compared.Result:Compared the folic acid levels,erythrocyte folate concentrations,plasma concentrations of folic acid and the lack rate of folic acid of two groups,the differences were no statistically significant(P>0.05). Serum progesterone values of two groups were compared,the differences were statistically significant(P<0.05).Conclusion:Serum progesterone values decreased speed and early outcome of threatened abortion have certain clinical relationship,but cannot think low blood folate levels as a risk factor for habitual abortion,and high levels of serum folic acid can reduce the risk of pregnant women with URSA.%目的：探讨分析血清检测同型半胱氨酸、叶酸、孕酮结果与习惯性流产之间的关系。方法：用病例对照研究方法，选取2014年5月-2015年5月至少有2次连续自然流产史的非孕期妇女62例作为习惯性流产组，选取同期在本院进行健康体检的62例孕妇作为参考组，对其同型半胱氨酸、孕酮以及叶酸等检测结果进行观察统计比较。结果：习惯性流产组的红细胞叶酸浓度、血浆叶酸浓度以及叶酸缺乏率同参考组进行比较，差异均无统计学意义（P>0.05）。两组的血清孕酮值比较，差异有统计学意义（P<0.05）。结论：血清孕酮值下降速度与早期先兆流产结局有一定的临床关系，但不能认为血液叶酸水平低下为习惯性流产的危险因素，而血清叶酸高水平可以使孕妇URSA发生的危险降低。