膀胱部分切除术与经尿道膀胱肿瘤电切术治疗非肌层浸润性膀胱癌的临床疗效分析

摘要

Objective:To investigate the effect of partial resection of bladder and transurethral resection of bladder tumor (TURBT) for treatment of superficial bladder cancer.Method:A total of 100 patients with T1T2 bladder neoplasm were randomly divided into two groups, each contained 50 cases.The control group was treated with partial resection of bladder, while the treated group was treated with TURBT.The operative time, blood loss, catheterization time, incidence of postoperative complication and recurrence rate was compared.Result:The operative time, blood loss, catheterization time of the observation group was significance of the indicators between the two groups (P<0.05). The incidence of postoperative complication of the observation group (2.1%) was significantly lower than that of the control group (16.8%) (P<0.05).There was no significant difference in the recurrence rate between the two groups. Conclusion:This study shows that the TURBT and partial resection of bladder have the similar recurrence rate.But TURBT has the advantage of shorter operative time, less trauma, less bleeding, faster recovery and low incidence of postoperative complication.%目的：研究膀胱部分切除术与经尿道膀胱肿瘤电切术（TURBT）治疗非肌层浸润性膀胱癌的临床疗效。方法：选取T1T2非肌层浸润性膀胱癌患者100例，随机数字表法分为治疗组和对照组各50例。对照组行膀胱部分切除术，治疗组行TURBT术，并对两组的术中出血量、手术时间、导尿管留置时间、术后并发症及复发率进行比较。结果：治疗组术中出血量（52.0±11.4）mL，手术时间（42.6±5.9）min，导尿管留置时间（2.2±0.4）d；对照组为（98.7±30.1）mL，（88.8±6.2）min，（4.7±1.0）d，两组比较差异有统计学意义（P<0.05）。治疗组术后出现并发症1例，发生率为2.0%，显著低于对照组的16.0%（8例），两组比较差异有统计学意义（P<0.05）。治疗组13例复发，复发率为26.0%，对照组14例复发，复发率为28.0%，两组比较差异无统计学意义。结论：膀胱部分切除术与TURBT治疗浅表性膀胱癌复发率相当，但TURBT术出血量少、手术时间短、恢复快、并发症少等优点，值得临床推广应用。