妊娠期与育龄期非妊娠妇女25-羟基维生素D水平的比较

摘要

ObjectiveTo study serum 25-hydroxyvitamin D [25(OH)D] levels in pregnant and non-pregnant childbearing age women,and to guide the basic healthy care for perinatal women.MethodsA total of 136 pregnant women and 122 non-pregnant childbearing age women were enrolled. The data,such as age,calcium supplements,multivitamin supplements and outdoor activity time per day,were collected through questionnaires. Serum 25(OH)D levels were determined by enzyme-linked immunosorbent assay(ELISA).ResultsThe levels of serum 25(OH)D were(45.40±13.26)nmol/L in pregnant group and(34.90±9.18)nmol/L in non-pregnant group(P<0.05). The proportions of vitamin D deficiency and insufficiency were 61.76％ and 37.50％ in pregnant group,and the proportions of vitamin D deficiency and insufficiency were 89.34％ and 10.66％ in non-pregnant group. ConclusionsPregnant women have higher serum 25(OH)D levels than non-pregnant childbearing age women. Vitamin D deficiency or insufficiency phenomenon is common.%目的 了解妊娠期与育龄期非妊娠妇女25-羟基维生素D[25(OH)D]水平,为围产期妇女营养保健提供依据.方法 选取136名妊娠期妇女(妊娠组)和122名育龄期非妊娠妇女(非妊娠组),通过问卷调查收集年龄、服用钙剂、服用复合维生素制剂及每天户外活动时间等资料.采用酶联免疫吸附试验(ELISA)检测血清25(OH)D水平并进行统计分析.结果 妊娠组血清25(OH)D水平为(45.40±13.26)nmol/L,明显高于非妊娠组[(34.90±9.18)nmol/L,P<0.05].妊娠组中有61.76％的妇女维生素D缺乏,有37.50％的妇女维生素D不足;非妊娠组有89.34％的妇女维生素D缺乏,10.66％的妇女维生素D不足.结论 妊娠期妇女25(OH)D水平高于育龄期非妊娠妇女.妊娠期与育龄期非妊娠妇女25(OH)D缺乏或不足现象均非常普遍.