早发型与晚发型新生儿败血症临床比较

摘要

Aim:To explore the early-onset and late-onset neonatal sepsis′clinical manifestations , blood test results and complications .Methods:A total of 60 patients with neonatal sepsis were collected and divided into early-onset group ( n=30 ) and late-onset group ( n=30 ) .For all the children , clinical manifestations , hematology associated results and complications were retrospectively analyzed .Results: The rates of hard swollen and lag in response in early-onset group were significantly higher than those of late-onset group(χ2 =12.273,5.963,P<0.05).The rates of septic shock and DIC in early-onset group were significantly higher than those of the late-onset group(χ2 =6.648,5.455,P<0.05), while the suppurative encephalitis incidence rate was lower (χ2adjusted =5.192,P=0.023).In early-onset group PLT was lower com-pared with the late-onset group(t=4.298,P<0.001).Conclusion:Early-onset and late-onset neonatal sepsis have dif-ferent clinical manifestations and auxiliary examination .%目的：探讨早发型与晚发型新生儿败血症的临床表现、血液检查结果及并发症发生情况的差异，为提高该病的诊断及治疗水平提供帮助。方法：选取2011年6月至2013年6月收治的新生儿败血症60例，分为早发型组和晚发型组，每组30例。对2组患儿的临床表现、血液学相关检查结果及并发症发生情况进行比较。结果：早发型组硬肿、反应迟钝发生率高于晚发型组（χ2＝12．273、5．963，P均＜0．05）。早发型组感染性休克、DIC发生率高于晚发型组（χ2＝6．648、5．455，P均＜0．05），而晚发型组化脓性脑炎发生率则高于早发型组（χ2校正＝5．192，P＝0．023）。早发型组PLT低于晚发型组（t＝4．298，P＜0．001）。结论：早发型与晚发型新生儿败血症临床表现、辅助检查各异，临床诊治过程中需综合分析。