不同类型弱视的图形视觉诱发电位波形分析

摘要

Objective To investigate the differences of pattern visual evoked potential (PVEP) waves of four kinds of amblyopia what are anisometropic amblyopia,ametropic amblyopia,strabismic amblyopia and high myopia with amblyopia.Methods PVEP waves of 40 asthenopic eyes were respectively analyzed and the amplitude of P100 waves and latencies were observed.Results Amplitude of P100 waves decreased obviously in each types of amblyopia.No direct correlations existed between the decrease of P100 amplitude and the visual acuity in the anisometropic amblyopia.The ametropic amblyopia,anisometropic amblyopia,strabismic amblyopia and high myopia with amblyopia were ordered according to the length of latency time.Conclusion The nerve conduction velocity is delayed in all types of amblyopia.There is less prolongation of P100 latency time in anisometropic amblyopia and ametropic amblyopia than that in optic neuritis,so it can distinguish the amblyopia from the optic neuritis.%目的 分析屈光参差性弱视眼、屈光不正性弱视眼、斜视性弱视眼、高度近视伴弱视眼的图形视觉诱发电位(PVEP)波形特性.方法 回顾性分析40例不同类型弱视眼的PVEP检查结果,观察P100波幅值及潜伏期的特点.结果 几种弱视眼的P100波幅值降低无明显规律,且屈光参差性弱视眼中P100波幅值降低程度与视力的降低程度无明显关系.潜伏期有一定程度延迟,按照由短到长的顺序排列为屈光不正性弱视、屈光参差性弱视、斜视性弱视、高度近视伴弱视.结论 弱视眼神经传导速度均有一定程度的变慢,按传导速度由快到慢的顺序排列为屈光不正性弱视、屈光参差性弱视、斜视性弱视、高度近视伴弱视.因单纯屈光不正性、屈光参差性弱视眼的潜伏期延迟较少,而球后视神经炎的P100波潜伏期延迟明显,可以作为鉴别诊断的参考.