目的 立足中国文化背景,编制针对辅助生殖女性患者心理症状与压力的评估工具.方法 基于文献研究并访谈65例患者,确定预期的量表结构,编制量表初始条目74个,在104例患者中施测并检验其信效度.结果 通过条目初筛、探索性与验证性因子分析得出保留条目52个,分为2个症状因子、6个压力因子;症状总分、压力总分及各因子分与抑郁量表、焦虑量表总分的相关系数0.38~0.85(P<0.01),表明量表效标效度良好;症状与压力分量表Cronbachα系数分别为0.93、0.96;ROC分析显示,症状分量表、压力分量表对临床焦虑/抑郁有较高的筛查价值,曲线下面积分别为0.93、0.92,临界分分别为30、74分.结论 所编量表有良好的信度、效度,可以作为辅助生殖女患者心理症状与压力的科学实用的评估工具.%Objective To develop a reliable and valid scale to assess mental stress and related symptoms for Chinese women undergoing assisted reproductive technology (ART) treatment. Methods Through literature research and in-depth interview with 65 ART patients, 74 initial items of the Symptom and Stress Inventory for Infertility (SSII) were developed. To evaluate psychometric properties of the SSII, 104 ART patients were asked to complete the initial scale, along with Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI). Results Principal component analysis with varimax rotation and confirmatory factor analysis identified 2 symptom-related factors and 6 stress-related factors, consisting of 52 items. Scores of symptom subscale, stress subscale and 8 factors were positively correlated with BAI and BDI scores (r=0.38~0.85, all P<0.01). Cronbach α for the symptom and stress subscales were 0.93 and 0.96, respectively. ROC analysis indicated the implication of the symptom and stress subscales for screening clinical anxiety/depression, with the values of area under the curve being 0.93 and 0.92, and the cutoff scores being 30 and 74, respectively. Conclusion The SSII demonstrates satisfactory psychometric properties and could be served as a useful psychological self-assessment tool for Chinese women undergoing ART treatment. Further refinement of this new scale in larger samples of ART patients and establishment of a norm are warranted for clinical practice.
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