饮食习惯与青年人膀胱移行细胞癌关系的病例对照研究

摘要

Objective:To investigate the relation of eating habit and patients with carcinoma of the bladder with 40 years old or younger. Methods: A case - control study was deployed. From January 1995 to August 2006,82 patients with age less than 40 with transitional cell carcinoma of the bladder treated at Shandong Provincial Hospital, Shandong Tumor Hospital and The Central Hospital of Feicheng Mining Group Company were selected as the case group( EG ), and another 82 young adult without bladder cancer as control group( CG ). X test was used for monovariate factor analysis while non - conditional logistic regression for multivariate analysis. Results: Non - conditional logistic regression for multivariate analysis displayed that the bladder cancer in patients younger than 40 was associated with the following factors: Irregular food and drink ( OR = 6. 117,95%CI:1. 079 -34.685 )milchigs intake( OR =0. 031,95% CI: 0. 002 - 0. 544 ). While monovariate analysis displayed that the bladder cancer in patients younger than 40 was associated with the following factors: regular food and drink, milk product intake, vegetable consumption, dietary soy. Conclusion: The bladder cancer in patients younger than 40 was associated with eating habit, regular food and drink, ordinarily intake milk products and vegetable, much water intake and less dietary soy may be the possible protective factors for patients younger than 40 of bladder cancer.%目的:探讨饮食习惯与青年人膀胱移行细胞癌的关系.方法:采用以人群为基础的1∶1病例对照研究,病例组为1995年1月1日至2006年8月31日山东省省立医院、山东省肿瘤医院、山东肥城矿业中心医院三家医院收治的40岁以下膀胱移行细胞癌患者,对照组为无膀胱癌的40岁以下青年人.病例组与对照组各82例.单因素分析采用χ2检验,多因素分析采用非条件Logistic回归分析.结果:多因素非条件Logistic 回归分析显示40岁以下膀胱癌患者与下列几种因素有关:饮食不规律(OR= 6.117,95%CI:1.079-34.685);食用奶制品(OR=0.031,95%CI:0.002-0.544).单因素分析显示40岁以下膀胱癌患者与下列几种因素有关:饮食规律、食用奶制品、食用蔬菜、饮水量、食用豆制品.结论:饮食习惯与40岁以下膀胱癌有关,合理规律饮食、常食用奶制品、多吃蔬菜、多饮水、少食豆制品可能减少40岁以下膀胱癌的发病机率.