摘要:Objective To analyze the correlation between the quality of life and symptoms of patients with gastroesophageal reflux disease, and syndrome of in-cordination between liver and stomach of patients with gastroesophageal reflux disease. Methods First assessed the patients who were diagnosed as gastroesophageal reflux disease (GERD) of their reflux related symptoms, symptoms of in-coordination syndrome between liver and stomach, as well as their quality of life, then analyzed the correlations of quality of life with reflux related symptoms and symptoms of in-coordination syndrome between liver and stomach by the method of linear correlation. Results There were statistic significance between the reflux related symptoms and quality of life in gastroesophageal reflux patients, including the domains of role physical, bodily pain, social functioning and mental health, of which the correlation coefficient are -0.25163, -0. 30000, -0. 23270, -0. 18180 respectively. Meanwhile, from the aspect of TCM, the correlations of quality of life with the in-coordination syndrome between liver and stomach had statistical significance, in cluding the domains of vitality, bodily pain, mental health, role physical, general health, social functioning, physical functioning , and role emotional, of which the correlation coefficient were - 0. 30080, -0. 28186, -0. 27572, -0. 26531, -0. 24416, -0. 23549, -0. 22667, -0. 20700 respectively. Conclusion Both reflux related symptoms and syndrome of in-coordination of liver and stomach can impair the life quality of GERD patients.%目的 分析胃食管反流病患者生存质量与反流相关症状、中医肝胃不和证症状的相关性.方法 对确诊为胃食管反流病的患者分别测评其反流相关症状、中医肝胃不和证症状及患者生存质量,并采用直线相关的方法分析生存质量与反流相关症状、中医肝胃不和证症状的相关性.结果 胃食管反流病患者生存质量在生理职能、身体疼痛、社会功能、精神健康四个维度上与反流相关症状的相关性有统计学意义,其相关系数(r)分别为:-0.25163,-0.30000,-0.23270,-0.18180.从中医学角度上看,患者的生存质量在活力、身体疼痛、精神健康、生理职能、总体健康、社会功能、生理功能、情感职能8个维度上与肝胃不和证症状有相关性,其相关系数(r)分别为:-0.30080,-0.28186,-0.27572,-0.26531,-0.24416,-0.23549,-0.22667,-0.20700.结论 反流相关症状及中医肝胃不和证症状的存在均可使胃食管反流病患者生存质量下降.