122例早产儿坏死性小肠结肠炎临床分析

摘要

Objective:To investigate the clinical manifestation ,causes and medical therapy of preterm necrotizing en‐terocolitis (NEC) ,so as to make early diagnosis and effective therapy ,and reduce the mortality .Methods:Retrospec‐tively analyze the clinical issues of 122 preterm infants whose gestational age is below 37 weeks with NEC from January 2010 to December 2015 .Results:From the analysis and comparison of the basic risk factors we find that there are signif‐icant differences in gestational age ,birth weight and breast feeding among these three stages ;Through observe the clin‐ical manifestations among these 122 cases ,we conclude that the incidence of abdominal distension ,vomiting ,gastric residuals and lethargy is much higher than blood stool;After the corresponding treatment ,the effective rate of stageⅠwas 100.0% ,the effective rate of stage Ⅱ was 94.0% ,the effective rate of stage Ⅲ was 75.0% .Conclusion:Early di‐agnosis and treatment is significant to reduce the mortality of NEC ;Timely and effective surgical interventions can im‐prove the prognosis of severe case .%目的：探讨早产儿坏死性小肠结肠炎（N EC ）的病因、临床表现及治疗，帮助实现早诊断及有效治疗，从而降低病死率。方法：回顾分析2010年1月－2015年12月我院新生儿重症监护室（N IC U ）收治的122例胎龄＜37周N EC患儿的临床诊疗情况。结果：对早产N EC患儿的基本发病因素进行对比分析，胎龄、出生体重及母乳喂养在三期患儿的差异有统计学意义；在122例患儿临床表现中，腹胀、呕吐、胃残留、反应低下的发生率高于血便；经治疗，Ⅰ期患儿总有效率为100．0％，Ⅱ期患儿总有效率为94．0％，Ⅲ期患儿总有效率为75．0％。结论：降低早产儿N EC的病死率需要早诊断、早治疗；及时有效的外科干预可提高严重N EC病例的治疗效果。