视神经脊髓炎脑部及脊髓影像学特征

摘要

目的 探讨视神经脊髓炎( neuromyelitis optica,NMO)患者脑部及脊髓MRI影像学表现及特征.方法 回顾性分析符合2006年Wingerchuk诊断标准23例NMO患者的脑部、脊髓MRI表现,分析NMO患者脑部及脊髓病灶的分布及信号特点.结果 典型的NMO脑内病灶位于脑室室管膜下、下丘脑及脑干等部位,表现为斑点、斑片及线状异常信号.5例脑部增强检查均未见异常强化病灶.NMO患者脊髓常呈长节段横贯性或次横贯性损伤,且以脊髓中央灰质受累为主,可见线样征.结论 NMO患者脊髓及脑部MRI出现异常信号有较特异的好发部位,病灶的分布有其自身特征.%Objective To investigate the MRI characteristics of brain and spinal cord in neuromyelitis optica (NMO). Methods 23 cases of NMO were examined by MRI. Distribution and signal features of all the lesions in brain and/or spinal cord were analyzed. Results Typical brain lesion locations included subependyma of ventricle, hypothalamus and brain stein. Post-contrast MRI showed no abnormal enhancement in 5 cases. The MRI characteristics of NMO patients in the spinal cord was linear lesion and longitudinally extensive transverse myelitis (LETM). and the distribution of spinal lesion usually was centric. Conclusion Brain and spinal cord abnormalities in NMO have characteristic positions. The observations of brain and spinal cord lesion are helpful to diagnose NMO.