核-壳型罗丹明6G磁性分子印迹固相萃取材料的合成与表征

摘要

采用化学共沉淀法制备 Fe3 O4磁性纳米粒子,以3-氨丙基三乙氧基硅烷(APTES)对其表面进行氨基硅烷化改性,形成 Fe3 O4＠SiO2-NH2纳米粒子.以其作为磁性核,采用表面印迹技术,以罗丹明6G 为模板,丙烯酰胺(AM)为功能单体,三羟甲基丙烷三甲基丙烯酸酯(TRIM)为交联剂,在 Fe3 O4＠SiO2-NH2表面形成罗丹明6G 分子印迹聚合膜,制备了核-壳型罗丹明6G 磁性分子印迹聚合物(Fe3 O4＠MIPs),对合成条件进行了优化.分别采用红外光谱(FT-IR)、场发射扫描电镜(FESEM )、振动样品磁强分析(VSM)和热重分析(TGA)等仪器分析手段,对 Fe3 O4＠MIPs的结构进行表征.结果表明,所制备的核-壳型磁性分子印迹聚合物具有高吸附容量及显著选择性；在外加磁场作用下Fe3 O4＠MIPs 可快速与样品基质分离,大大提高了实验效率.Fe3 O4＠MIPs 作为一种新型固相萃取材料,可以从样品中选择性分离和富集违规添加的罗丹明6 G,可应用于食品的安全检测.%Fe3 O4 magnetic nanoparticles were synthesized by the chemical co-precipitation method.With (3-aminopropyl)triethoxysilane (APTES)on the surface modification,Fe3 O4 @SiO2-NH2 nanoparticles were formed.Core-shell magnetic molecularly imprinted polymers (Fe3 O4@MIPs)were prepared by using Rhoda-mine 6G as template molecule,acrylamide (AM)as functional monomer,trimethylolpropane trimethacrylate (TRIM)as cross-linking agent,and amino-modified Fe3 O4 magnetic nanoparticles as the magnetic core.The Fe3 O4@MIPs were characterized using a Fourier transform infrared spectrometer(FT-IR),field emission scan-ning electron microscope (FESEM),vibrating sample magnetometer(VSM),and thermogravimetric analysis (TGA).The Fe3 O4@MIPs showed a highly improved imprinting capacity and significant selective;they could be used as solid-phase extraction material and applied to the safety detection of illegal add Rhodamine 6G in foods.