唾液MMP-2和MMP-9含量与4～5岁儿童龋病相关性的研究

摘要

目的:初步探讨4~5儿童唾液中MMP-2和MMP-9含量与龋病的关系.方法:以无龋组、低龋组、高龋组儿童各33名为研究对象,采用 ELISA法检测唾液 MMP-2和 MMP-9含量,并进行统计学分析.结果:唾液MMP-2含量:无龋组<低龋组<高龋组,各组间差异均有统计学意义(P<0.05);唾液MMP-9含量:无龋组<低龋组<高龋组,各组间差异均有统计学意义(P<0.05).结论:随着龋病严重程度的增加,唾液MMP-2和MMP-9含量呈上升趋势.唾液MMP-2和MMP-9可能在龋病进展中发挥作用.%Objective:To investigate the relationship among children aged 4 ~5 years,between dental caries and MMP-2 and MMP-9 levels in saliva.Methods:Thirty-three children were randomly selected for each group that caries-free group,low caries group and high caries group.The levels of MMP-2 and MMP-9 were examined by ELISA.The results were statistically analyzed.Results:The difference of saliva MMP-2 levels was statistically significant among three groups:caries-free group