The to fluorescent indicator which is obtained sialic acid, by the fluorescent labeling manner, and aforementioned manner of the sialic acid content sugar or the sialic acid content complex carbohydrate the sialic acid which is converted, the sialic acid content sugar or the sialic acid content complex carbohydrate

摘要

PPROBLEM TO BE SOLVED: To provide a method for efficiently fluorescent-labeling sialic acid, sialic acid-containing glucide, or sialic acid-containing glycoconjugate, which enables the highly sensitive analyses of the sialic acid-containing glucide or the sialic acid-containing glycoconjugate by various analysis means such as various chromatography and mass spectrometry, and to provide the fluorescent-labeled sialic acid, sialic acid-containing glucide, or sialic acid-containing glycoconjugate, obtained by the method. PSOLUTION: Provided are the method for efficiently fluorescent-labeling the sialic acid, sialic acid-containing glucide, or sialic acid-containing glycoconjugate, characterized by binding a compound represented by general formula (1), wherein (n) is an integer of 2 to 4, to the carboxy group of the sialic acid in at least one of the sialic acid, the sialic acid-containing glucide, and the sialic acid-containing glycoconjugate; and the fluorescent-labeled sialic acid, sialic acid-containing glucide, or sialic acid-containing glycoconjugate sialic acid, obtained by the method. PCOPYRIGHT: (C)2009,JPO&INPIT