福建省重性抑郁障碍流行病学调查

摘要

Objective:To study the point prevalence of major depressive disorder (MDD) in Fujian provrnince and its possible influence factors. Method: 10 000 persons more than 15 years old were randomly selectrned as investigation subjects by multi-stage stratified cluster sampling approach. A modified version of general rnhealth questionnaire (GHQ-12) was used as the screen tool and structured clinical interview for DSM-IV-TR rnAxis Ⅰdisorder-Patient edition (SCID-I/P) was used as the diagnosis tool. Results:The point prevalence of rnMDD was 3.35％ (95％ CI = 2.99％ ～ 3.70％ ), with female and male 4.34％ and 2.42％, respectively ( x2 =rn18.65,P＜0.01). The point prevalence in urban areas was higher than rural areas (5.13％ vs. 2.41％ ,x2 =rn11.86,P ＜ 0.01 ) ,among them mainly aged between 50 and 59 with point prevalence 10.08％. Conclusion:rnThe prevalence prevalent trend and distribution feature of MDD in Fujian province were similar to the most other rnareas in China. It had its own characteristics which should be paid more attention to when making programs for rnmental health prophylaxis and treatment.%目的:了解福建省重性抑郁障碍患病率,探讨可能的影响因素.方法:采用多阶段分层整群抽样方法,随机抽取10 000名≥15岁的个体为调查对象,以改编后的一般健康问卷12项(GHQ-12)为筛选工具;以美国精神障碍诊断与统计手册第4版轴I障碍定式临床检查患者版(SCID-I/P)为调查的诊断工具.结果:福建省重性抑郁障碍时点患病率为3.35%(95%CI=2.99%～3.70%);女性患病率(4.34%)高于男性(2.42%)(χ2=18.65,P<0.01);城市患病率(5.13%)高于农村(2.41%)(χ2=11.86,P<0.01).其中以50～59岁年龄段患病率(10.08%)最高.结论:福建省重性抑郁障碍的患病率、流行趋势和分布规律与中国大多数地区的结果相似,危险因素有自身特点,今后在制定精神卫生防治规划时需予以重视.