免疫调节药物在1型糖尿病中的研究进展及应用前景

摘要

1型糖尿病是一种自身免疫性疾病,其病理特征为免疫治疗提供了明确的理论依据.免疫调节药物作为1型糖尿病重要的免疫治疗方法,作用于自身免疫进程的不同环节,在胰岛β细胞功能保护方面体现了一定价值.本文将对近年免疫调节药物在1型糖尿病预防及治疗中的最新研究进展作一综述并提出展望.%The pathophysiological nature of type 1 diabetes mellitus (T1DM) as an autoimmune disease provides the basis for immunotherapy.As an important therapeutic approach,immunomodulatory drugs are promising in the protection of pancreatic β-cells by effecting at various stages of autoimmune progression.In this review,we summarize the recent advances of immunomodulatory drugs in the prevention and treatment of T1DM and propose future directions.