肌张力障碍门诊患者的临床特点分析

摘要

Objective To investigate the characteristic of movement disorders,so as to improve their diagnosis and treatment. Methods The clini⁃cal data of patients with movement disorders that admitted in the dystonia and Botox outpatient department were analyzed. Results Cases of involun⁃tary movement were significantly more than the primary dystonia,and case of primary hemifacial spasm was dominant(163 cases,61.05%). Among the 66 cases of primary dystonia,blepharospasm was ranked the first(19 cases),the second was spasmodic torticollis(18 cases),and the third was Meige syndrome(12 cases).There was no statistical significance in the gender distribution among primary hemifacial spasm,blepharospasm,spas⁃modic torticollis and Meige syndrome. Instead,there was statistical significance in the treatment methods(P<0.05),and there was statistical signifi⁃cance in the mean treatment and onset age(P<0.05). Of the 163 cases with primary hemifacial spasm,the mean onset age was 44.22±12.22 years, and the ratio of men to women was 1∶2.4. There were statistical significances in the mean onset age and duration among the patients with different severity degrees(all P<0.05). Conclusion Primary hemifacial spasm,blepharospasm,spasmodic torticollis and Meige syndrome are the com⁃mon disease in outpatient department. The primary hemifacial spasm is dominant,women are more than men,and the onset age and/or duration are proportional to the severity degree.%目的：认识运动障碍疾病及其特点，以提高诊治水平。方法分析我院肌张力障碍及肉毒毒素治疗门诊登记的运动障碍患者的临床资料。结果不自主运动的病例明显多于原发性肌张力障碍，原发性偏侧面肌痉挛病例占绝对优势（163例，61.05%）。66例原发性肌张力障碍中排在前3位的是眼睑痉挛（19例）、痉挛性斜颈（18例）、Meige综合征（12例）。常见的原发性偏侧面肌痉挛、眼睑痉挛、痉挛性斜颈及Meige综合征中，性别分布差异无统计学意义，不同治疗方法差异有统计学意义（P<0.05），平均就诊年龄和平均发病年龄差异有统计学意义（P<0.05）。在163例原发性偏侧面肌痉挛患者中，平均发病年龄为（44.22±12.22）岁，男女比为1∶2.4；在不同病情程度的患者中，平均发病年龄和病程差异有统计学意义（P<0.05）。结论我院门诊常见的运动障碍疾病为原发性偏侧面肌痉挛、眼睑痉挛、痉挛性斜颈及Meige综合征。其中原发性偏侧面肌痉挛占绝对优势，女性多于男性，发病年龄和（或）病程与病情程度呈正比。