Objective The aim of this paper was to investigate the reliability and validity of the Chronic respiratory disease questionnaire (CRQ) in China. Method Sixty-eight patients with chronic respiratory disease who were in hospital from January to November, 1999 were surveyed with CRQ. Eighteen patients were investigated repeatly with CRQ in one week to test the reliability; before and the 10th day after treatment, 50 patients were surveyed twice with CRQ and the peakflow of these patients were also detected. The same doctor explained questionnaires and tested peakflow. Results The correlated analysis of reliability was positive (r=0.732, P<0.01). The correlatied analysis between the difference of twice-questionnaire scores and the difference of twice-peakflow value was also positive (r=0.565, P<0.01).Conclusion CRQ can be used by the clinical doctors of China.%目的：了解慢性呼吸系统疾病问卷（CRQ）在我国临床应用的信度（一致性）和效度（可靠性）。方法：对68例慢性肺疾病病人进行问卷调查，其中18例在1周内进行试验-再试验可靠性调查，另50例患者分别于治疗前、后10 d发放问卷调查，同时，分别测定其峰流速值，对其变化值进行相关性分析。结果：信度比较，二次问卷调查相关性分析，分值呈正相关（r=0.732, P<0.01）,效度相关性分析，差值呈正相关（r=0.565, P<0.01）。结论：CRQ在我国应用有一定的临床意义。
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