57例三阴性乳腺癌的临床病理特征分析

摘要

目的：探讨三阴性乳腺癌（ TNBC）的临床病理特征。方法回顾性分析57例TNBC患者的临床资料，并以280例非三阴性乳腺癌患者（ NTNBC）作为对照。结果 TNBC组Ⅲ级28例（49.1%），NTNBC组12例（4.3%）（P<0.05）。局部复发率在TNBC组及NTNBC组中分别为15.8%及6.8%（P<0.05）；远处转移率分别为26.3%及14.6%（P<0.05）。结论乳腺癌TNM分期能够反映TNBC的侵袭性和复发转移的临床特点，TNBC患者更易出现淋巴结转移及远处转移。%Objective To analyze the clinicopathological features of the patients with triple negative breast canc-er. Methods The data of 57 patients with triple negative breast cancer( TNBC)were analyzed retrospectively,and the 280 patients with non-triple negative breast cancer( NTNBC)were the control group. Results The patients with grade Ⅲ were 28 patients(49. 1%)in the TNBC group,and were 12 patients(4. 3%)in the NTNBC group (P<0. 05). The local recurrence rate was 15. 8% in the TNBC group,and was 6. 8% in the NTNBC group(P<0. 05);the metastasis rate was 26. 3% and 14. 6%,retrospectively(P<0. 05). Conclusion The TNM staging system for breast cancer can reflect the features of invasion,recurrence and metastasis of TNBC,TNBC has the high metastasis rate.