目的 比较分析原发性低钾性周期性麻痹与甲状腺毒症继发周期性麻痹的异同点、临床特征,以便提高诊治水平.方法 选择低钾性周期性麻痹患者45例,回顾性分析其临床资料.结果 45例低钾性周期性麻痹患者中,原发性低钾性周期性麻痹28例(A组),甲状腺毒症继发周期性麻痹17例(B组);两组患者在性别、临床表现、诱因、肌酸激酶、补钾时的剂量与血钾水平均没有关系等方面具有共同点.两组患者的高代谢症状、血钾水平、反弹性高钾血症的出现等方面存在不同之处.结论 低钾性周期性麻痹有其临床特点.预后关键在于早期诊断和及时补钾.补钾剂量不可以根据发病时血钾水平定量,以及甲状腺毒症继发周期性麻痹在补钾过程中容易出现反弹性高钾血症,所以要密切监测血钾水平,并积极根治甲状腺毒症.%Objective To compare and analyze the similarities and differences , clinical features on the primary hypokalemic periodic paralysis and thyrotoxicosis secondary onset periodic paralyses, so as to improve the level of diagnostic treatment. Methods 45 cases of hypokalemic periodic paralysis patients were chosen, with clinical data retrospectively analyzed. Results Among 45 hypokalemic periodic paralysis patients, there are 28 primary hypokalemic periodic paralysis patients (for Group A) and 17 thyrotoxicosis secondary onset periodic paralyses patients (for Group B), the gender, clinical manifestation, occasion, creatine kinase and the relation of dosage of potassium with the level of hypokalemia in the two groups are common. The differences of them are hypermetabolism symptom, the level of hypokalemia and elastic recoil hyperpotassemia. Conclusion The hypokalemic periodic paralysis has its clinical features, with the key points of early diagnosis and the potassium supply. The dosage of supplying the potassium can' t be amounted according to the level of hypokalemia, and during the progress of supplying potassium, it' s easy to appear the elastic recoil hyperpotassemia, so shoud pay attention to the monitoring survey about the level of hypokalemia, and to treat thyrotoxicosis energetically.
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