Objective To provide scientific evidences for prenatal examination and human aristogenesis and good brood by studying the morbidity of thalassemia and G6PD deficiency of newly-born infants in Taishan City. Methods Using mOB-vesset screen method of thalassemia and by the means of enzymology to detect thalassemia and G6PD deficiency for 1871 newly-born infants in Taishan City. Results Among 1871 infants, detection rate discern of thalassemia and G6PD deficiency was 9.0 % and 6.9%. In 955male infant cases, thalassemia was 88 cases and G6PD deficiency was 70 cases ,detection rate discern was 9.2% and 7.3 %, while in 916 female infant cases, thalassemia was 81 cases and G6PD deficiency was 60cases, detection rate discern was 8.8 % and 6.5% .The result showed no obvious difference between male and female infants. Conclusion There is higher morbidity of thalasemia and G6PD deficiency in newly born infants in Taishan City. Premarital and prenatal detection of thalassemia and G6PD deficiency should be strengthened and scientific guidance of aristogenesis and good brood should be provided.%目的 了解台山地区新生儿地中海贫血和G6PD缺乏的发病率,为产前检查和优生优育工作提供科学依据.方法 应用地中海贫血一管筛查法和G6PD定量测定酶法检测1871名新生儿的地中海贫血和G6PD缺乏情况.结果 1871名新生儿的地中海贫血和G6PD缺乏的总检出率分别为9.0%和6.9%.其中,955例男婴中,地中海贫血检出88例,G6PD缺乏70例,检出率分别为9.2%和7.3%;916例女婴中,地中海贫血检出81例,G6PD缺乏60例,检出率分别为8.8%和6.5%.男女间的差异均无显著性.结论 台山地区新生儿的地中海贫血和G6PD缺乏发病率较高,应加强婚前检查和产前筛查,并进行优生优育的科学指导.
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