舒血宁联合多烯磷脂酰胆碱对慢性乙型病毒性肝炎患者丙氨酸氨基转移酶及总胆红素的影响

摘要

Objective To investigate the effect of Shuxuening combined with Polyene phosphatidylcholine injection on ALT and TBiL in chronic viral hepatitis B. Methods 84 cases of chronic hepatitis B were randomly divided into two groups. 42 patients in control group were treated by polyene phosphatidylcholine injection. 42 cases in treatment group were treated by combination of polyene phosphatidylcholine injection and Shuxuening injection. The therapeutic course was one week in two groups. The changes of ALT and TBiL were observed before and after of one and two weeks treatment. Results ALT and TBiL after of one and two weeks treatment were obviously decreased compared with those before treatment in treatment group ( P ＜ 0.05 ). There were obvious differences between two groups on ALT and TBiL after of one and two weeks treatment ( P ＜ 0.05). Conclusion Shuxuening combined Polyene phosphatidylcholine injection can decrease the ALT and TBiL and improve liver function and jaundice in patients with chronic viral hepatitis B.%目的 观察舒血宁注射液联合多烯磷脂酰胆碱注射液对慢性乙型病毒性肝炎患者丙氨酸氨基转移酶(ALT)及总胆红素(TBiL)的影响.方法 将84例慢性乙型病毒性肝炎患者随机分为2组,对照组42例予多烯磷脂酰胆碱注射液,治疗组42例在对照组的基础上予舒血宁注射液.2组均1周为1个疗程,治疗2个疗程.观察2组治疗前、治疗后1、2周未ALT、TBiL变化情况.结果 治疗组治疗后1、2周末ALT、TBiL与本组治疗前比较均明显下降(P<0.05).治疗组治疗后1、2周未ALT、TBiL与对照组同期比较差异均有统计学意义(P<0.05),治疗组疗效优于对照组.结论 舒血宁注射液联合多烯磷脂酰胆碱注射液可通过降低ALT、TBiL改善慢性乙型病毒性肝炎患者肝功能和黄疸症状.