Objective To investigate the cognitive status on prenatal screening and diagnosis of Down's syn-drome (DS) in Shanwei, and to summarize the influencing factors. Methods Five hundred pregnant women in our hos-pital during the period from January 2015 to January 2016 were selected and investigated by the self-designed question-naire. A total of 475 valid questionnaires were collected. The results were statistically analyzed. Among the 475 cases, 313 cases with good cognition on DS prenatal screening and diagnosis were enrolled as the observation group, and other 162 cases were included into the control group. Chi-squared test was used to analyze the factors affecting the cognitive status of DS prenatal screening and diagnosis. Results In the 475 cases of pregnant women, the awareness rate of DS and DS screening was 84.84%and 83.79%, and 250 cases (79.87%) in the observation group understood DS through the doctor. The proportions of pregnant women with high-school education or above and the pregnant women monthly per capita income≥4000 yuan in observation group were 61.66% and 43.13%, which were significantly higher than 51.23% and 28.40% in the control group (P<0.05). The pregnant women with higher education level, better economic conditions tended to have better cognition on DS prenatal screening and diagnosis. Conclusion The family income and education level are the main factors that influence the cognition on DS prenatal screening and diagnosis. Medical staff should strengthen the health education on pregnant women with lower economic income and education level.%目的 探讨汕尾地区孕妇对唐氏综合征(DS)产前筛查与诊断的认知情况,并探讨其影响因素.方法 选择2015月1月至2016年1月期间我院门诊产前检查的500例孕妇为调查对象,采用自行设计的调查问卷进行调查,其中有效调查问卷475份,对调查结果进行统计学分析;将313例对DS产前筛查与诊断认知程度佳者纳入观察组,余162例认知不佳者纳入对照组,采用卡方检验分析影响DS产前筛查与诊断的认知情况的相关因素.结果 475例孕妇对DS及DS筛查知晓率分别为84.84%、83.79%;观察组孕妇通过医生了解DS者250例,占79.87%;观察组孕妇高中以上学历者占61.66%、月人均收入≥4000元者占43.13%,均明显高于对照组的51.23%和28.40%,差异均有统计学意义(P<0.05),即文化程度越高、经济条件越好的孕妇其对DS产前筛查与诊断认知程度越高.结论 家庭经济状况及文化程度是影响唐氏综合征筛查与诊断认知的主要因素,应当加强对经济收入及文化程度低的孕妇的健康教育,并且重视医务人员对孕妇的健康教育.
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