17β-雌二醇乙酸纤维分子印迹复合膜的制备及性能研究

摘要

In this paper,the 17β-Estradiol molecularly imprinted composite membrane through UV initiation was prepared by using porous cellulose acetate membrane as support.The selective binding properties and separation capacity of the membranes were investigated.The results showed that the 17β-Estradiol molecularly imprinted composite membrane had high binding capacity for 17β-Estradiol,the binding amount Q for 17β-Estradiol was 10.2 μmol/g and separation factor was 4.7 for 17β-Estradiol/17α-ethinylestradiol.Permeation experiment results showed that the molecularly imprinted composite membrane could separate 17β-Estradiol from 17α-ethinylestradiol.The bonding force between 17α-ethinylestradiol and the membrane was weaker than the template.%以多孔乙酸纤维膜为载体,17β-雌二醇为模板,采用紫外光引发制备了17β-雌二醇乙酸纤维分子印迹复合膜。试验对膜的选择吸附性和分离透过性进行了探讨。实验结果表明,所合成的乙酸纤维分子印迹复合膜对模板分子17β-雌二醇具有较好的选择吸附性,吸附量达10.2μmol/g;17β-雌二醇/17α-炔雌醇的分离因子为4.7。膜透过实验表明,该分子印迹复合膜能将17β-雌二醇与17α-炔雌醇分离开,表明17α-炔雌醇作为结构类似物在复合膜上的结合牢固性不如模板分子。