高效液相色谱法测定PC奶瓶中双酚A的含量及其迁移量

摘要

A high performance liquid chromatographic (HPLC) method was developed for determining bisphenol A (BPA) residue and migration in polycarbonate (PC) baby milk bottles. Solid-phase extraction (SPE) for analyte enrichment was used to study the effect of soaking time on BPA migration from PC baby bottles. BPA residues were detected in a certain brand of baby bottle at a level of 10.7 mg/kg. The migration of residual BPA from PC baby bottles to water reached the maximum level after exposure for 1–6 h, showed no obvious changes with increasing exposure time and basically reached equilibrium after 10 h exposure. During the whole process, the specific migration amount of BPA was 0.36 mg/kg, and the final concentration in water was 0.025 mg/L. The limit of detection of the HPLC method was 0.6 ng/mL (RSN=3). The average recovery rates of BPA across three spike levels were 85.9%–89.5%with a relative standard deviation (RSD) of 0.78%–1.43%(n=4).%建立高效液相色谱法对PC奶瓶中残留双酚A(BPA)含量的检测方法，并以水为模拟液，固相萃取法富集处理，研究不同浸泡时间BPA的迁移变化规律。结果表明：市售某品牌PC奶瓶内可检测到BPA，其总残留量为10.7mg/kg；对PC奶瓶中残留BPA向水样中迁移的检测表明在1～6h内BPA迁移率为最大，6h后迁移量变化不明显，10h后基本到达饱和，整个过程中BPA的特定迁移量为0.36mg/kg，在水中的终质量浓度为0.025mg/L。该方法检测限(RSN=3)为0.6ng/mL，回收率在85.9%～89.5%之间，相对标准偏差0.78%～1.43%。