川明参咀嚼片配方与制备工艺研究

摘要

To study the formulation and preparation technology of Chuanmingshen chewable tablets. To decide the dosage of each filler by the single factor test , the formulation and preparation technology of Chuanmingshen chewable tables were screened by orthogonal test and multi-index test. As a result , the optimized formulation was as follows:sorbitol 25%,lactose5%,citric acid 0.5%,dextrin 10%,avicel 28.5%,magnesium stearate 1.0%,extract of Chuanmingshen 30%. The prepared Chuanmingshen chewable tablets had the smooth surface , uniform color, suitable hardness and good taste. The optimized preparation process is simple and practical.%研究川明参咀嚼片的配方和工艺。以多指标感官评定为依据，采用单因素试验考察各填充剂用量，采用正交试验优化配方，筛选川明参咀嚼片最佳配方。结果表明川明参咀嚼片的最佳配方为：山梨醇25%，乳糖5%，柠檬酸0.5%（酸味剂），糊精10%，微晶纤维素28.5%，硬脂酸镁1.0%（润滑剂），川明参浸膏30%。该配方工艺简便，实用性强，所制得的川明参咀嚼片酸甜适宜，且入口顺滑细腻，咀嚼性强。