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EXCIPIENT BASE FORMULA, CHEWABLE FORMULA CONTAINING THE SAME, AND THE METHOD OF MAKING CHEWABLE TABLET

机译:赋形剂基础配方,包含相同配方的可咀嚼配方以及可咀嚼片剂的制备方法

摘要

An excipient base formula for chewable tablet comprises from about 15% to about 55% by weight of xylitol; from about 20% to about 45% by weight of inulin; from about 1% to about 4% by weight of flowing agent; and from about 1% to about 4% by weight of lubricant based on the total weight of the excipient base formula. A chewable formula comprises at least one active ingredient and said excipient base formula, wherein inulin is not considered as the active ingredient. The chewable formula is suitable for a direct compaction to produce chewable tablet.
机译:用于可咀嚼片剂的赋形剂基础配方包含按重量计从约15%至约55%的木糖醇;优选地,所述可吸收片剂的赋形剂包括:菊粉重量的约20%至约45%;按重量计约1%至约4%的流动剂;基于赋形剂基础配方的总重量,润滑剂的量为约1%至约4%重量。咀嚼型配方包含至少一种活性成分和所述赋形剂基础配方,其中菊粉不被视为活性成分。可咀嚼的配方适合直接压实以生产可咀嚼的片剂。

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