研究发酵前后金丝小枣多糖对缓解小鼠体力疲劳的影响.取56只雄性 SPF级昆明小鼠,连续灌胃不同剂量的枣多糖,4周后分别测定小鼠体重、力竭游泳时间以及相关抗疲劳评价指标.结果表明,与对照组相比,发酵前后的金丝小枣多糖均能延长小鼠力竭游泳时间(发酵前的高剂量组和发酵后的中剂量组的延长率分别为32.01%,47.98%),提高肝糖原和肌糖原含量、谷胱甘肽过氧化物酶和超氧化物歧化酶活力,降低尿素氮和血乳酸含量、肌酸激酶活力,发酵多糖中剂量组小鼠各项指标的测定结果均有极显著差异.发酵前后的金丝小枣多糖均具有缓解小鼠体力疲劳的作用,而且发酵后中剂量对小鼠体力疲劳的缓解作用更加明显.%The effects of fermented and unfermented Ziziphus jujuba polysaccharide on the physical fatigue alleviation in mice was investi-gated in this study.5 6 male SPF class Kunming mice were fed with different doses of polysaccharides,and their body weight,exhaustive swimming time and related anti-fatigue evaluating indexes were measured after treated for 4 weeks.Tests showed that,compared with the normal control group,the mice fed with the polysaccharides from fermented and unfermented Ziziphus jujuba had a prolonged ex-haustive swimming time.The percentage elongation was 32.01% for the high-dose unfermented jujuba polysaccharide treated group,and the percentage elongation was 47.98% for the medium dose of the fermented one.The effect of the medium-dose fermented jujuba poly-saccharide on alleviating physical fatigue was remarkable,and the content of hepatic glycogen and muscle glycogen,and the activities of glutathione peroxidase and superoxide dismutase increased. Moreover,the content of urea nitrogen,lactic acid and the activity of creatine kinase decreased.The polysaccharides from both fermented and unfermented Ziziphus jujuba had the effect of relieving the physi-cal fatigue in mice,and the effect of medium-dose of the fermented group on alleviating physical fatigue was more remarkable.
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