萍乡市10岁以下儿童疫苗针对疾病抗体水平监结果分析

摘要

目的：了解萍乡市10以下儿童麻疹、风疹、乙脑、甲肝、乙肝表面抗原和抗体水平，为制定和完善相应的预防策略提供依据。方法：选择10岁不同年龄组健康人群作为监测对象，采用酶联免疫吸附试验检测人群麻疹、风疹、乙脑、甲肝、乙肝表面抗原和抗体。结果：共检测307儿童，麻疹阳性标本259份，麻疹IgG抗体阳性率84.36％，各年龄组之间差异有统计学意义(χ2=62.105，P0.05)；甲肝阳性标本204份，甲肝IgG抗体阳性率为66.45％，各年龄组之间差异无统计学意义(χ2=12.005，P>0.05)；乙肝表面抗体阳性率为82.74％，各年龄组之间差异无统计学意义(χ2=1.273，P>0.05)，乙肝表面抗原携带率为10.42％，各年龄组之间差异无统计学意义(χ2=4.869，P>0.05)。各抗体水平无性别差异。城区与农村地区，除甲肝抗体差异无统计学意义外，其他抗体差异均有统计学意义。结论：萍乡市10岁以下儿童麻疹、乙脑、乙肝抗体水平免疫状况良好，IgG 抗体阳性率均在80%以上，风疹、甲肝IgG抗体阳性率偏低，须加强重点地区、重点人群的预防接种工作，必要时开展补充免疫工作。%Objective: To understand measles, rubella, encephalitis, hepatitis A, hepatitis B surface antigen and antibody level in the serum of Pingxiang children with in 10 years old, to provide the basis for the development and perfection of the corresponding preventive strategy.Methods: 10 different age groups of healthy persons were chosen as the monitoring object. ELISA was used to detect the population of measles and rubella, encephalitis, hepatitis A, hepatitis B surface antigen and antibody.Results: A total of 307 children with measles were detected, 259 specimens were positive, the positive rate of measles IgG antibody in 84.36%, there were statistically significant differenc es between different age groups (χ2=62.105,P0.05); a 204 specimens were positive, the positive rate of anti hepatitis A IgG was 66.45%, between each age group the difference was statistically significant (χ2=12.005,P>0.05); the positive rate of hepatitis B the surface antibody was 82.74%, there was no significant difference between different age groups (χ2=1.273,P>0.05), hepatitis B surface antigen carrying rate was 10.42%, there was no significant difference between different age groups (χ2=4.869,P>0.05). There were no gender differences in antibody levels. The urban and rural areas in addition to hepatitis A antibody antibody had no significant difference in other external differences were statistically significant.Conclusion: The measles, children under the age of 10 Japanese encephalitis, hepatitis B antibodies in immune condition, IgG antibody positive rate was above 80%, the positive rate of IgG antibody of rubella, hepatitis A is low, must strengthen key areas and populations of the vaccination work, carry out supplementary immunization work when necessary.