慢性肾脏病住院患者降压药物的使用研究

摘要

目的：回顾性调查合并有高血压的住院慢性肾脏病患者降压药的使用，为临床合理用药提供依据。方法：调查2014年我院肾内科住院的合并有高血压的慢性肾脏病患者共196例进行统计分析。结果：67.35%患者使用联合降压方案，其中30.61%的患者两药联用，21.94%的患者三药联合。在降压药的选择上，使用频率最高的为RAS阻断剂(包括ACEI和ARB)，占78.57%；其次为钙离子拮抗剂类降压药,占66.84%。结论：慢性肾脏病的高血压患者联合应用降压药的比例很高，临床应用时应密切随访，以避免不良反应的发生。%Objective: To investigate management and control of hypertension in hospitalized patients with chronic kidney disease and hypertension, and to provide reference for rational use of drugs.Methods: 196 patients with CKD and hypertension who hospitalized in our hospital urology department from 2014 were studied.Results: 67.35% patients were treated with a combined antihypertensive plan, in which, 30.61% patients used two kinds of drugs combination, and 21.94% patients used three kinds of drugs combination. Renin-angiotensin system(RAS) inhibitors(including ACEI and ARB) were the most frequently prescribed drug, taken by 78.57% patients, followed by CCB 66.84%.Conclusions: CKD accounts for a high proportion of combined use of antihypertensive drugs in hypertensive patients, thus the clinical application should be closely followed up, to avoid the occurrence of adverse reactions.