Objective To summarize the clinical characteristics of endometrial carcinoma patients of Beijing Obstetrics and Gynecology Hospital in recent 20 years and analyze the change trend , so as to better screen endometrial carcinoma and provide evidence for making standard principle of diagnosis and treatment. Methods A total of 1 213 Beijing cases of endometrial carcinoma treated in Beijing Obstetrics and Gynecology Hospital from 1992 to 2011 were studied from 4 phases (1992 - 1996, 1997 -2001, 2002 -2006 and 2007 -2011). The relative ratio of endometrial carcinoma and cervical cancer , onset age, pathological type and surgery stage were analyzed . Results The relative ratio of endometrial carcinoma and cervical cancer increased from 45. 40% to 49. 81% , and the ratio of patients aged 40 years and younger increased from 6. 76% to 9. 59% . Ratio of type Ⅰ endometrial carcinoma declined from 87. 16% to 82. 78% . Ratio of stage Ⅰ cases increased from 59. 17% to 69. 48% , and that of stage Ⅲ cases decreased from 29. 17% to 16. 27%. Ratio of stage Ⅰ cases in patients aged 40 years and younger was 81.48%. Conclusion The constituent ratio of endometrial carcinoma and cervical carcinoma has gone up, and the rate of young patients has been elevated . Type Ⅰ still takes the most important role in all the pathological types of endometrial carcinoma, but the ratio of type Ⅱ has gone up. There is a significant increase of early stage cases . At the same time the number of late stage cases decreases. Most of the young patients are stage Ⅰ endometrial carcinoma , which makes it possible to conserve fertility and ovarian function. Late stage cases increase with age , which tells us that it is important for old endometrial carcinoma patients to be early found, diagnosed and treated.%目的 总结北京妇产医院20年子宫内膜癌的发病特点,分析其变化趋势,以便更好开展对子宫内膜癌的筛查,为制定更加规范的子宫内膜癌诊疗原则提供依据.方法 将1992至2011年北京妇产医院收治的北京市籍1 213例子宫内膜癌患者分4个阶段(1992至1996年、1997至2001年、2002至2006年、2007至2011年)进行统计,分析子宫内膜癌与子宫颈癌发病相对比、发病年龄、病理类型、手术分期等变化趋势.结果 子宫内膜癌的相对比由45.40%升至49.81%.≤40岁患者比例由6.76%升至9.59%.Ⅰ型子宫内膜癌所占比例由87.16%降至82.78%.Ⅰ期病例由59.17%升至69.48%,Ⅲ期病例由29.17%降至16.27%.≤40岁患者Ⅰ期病例占81.48%.结论 子宫内膜癌与子宫颈癌相对比有升高趋势,年轻患者所占比例上升.病理类型仍以Ⅰ型为主,随着患者年龄增加晚期病例增多,提示对老年子宫内膜癌患者应做到早发现、早诊断、早治疗.
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