维生素D2-A和CD片段醇的合成工艺改进

摘要

以维生素D2(V-D2)为原料,经高锰酸钾氧化、选择性切断和还原反应同时合成了维生素D2-A(总产率30%)和CD片段醇(总产率45%),其结构经1 H NMR确证.%Both vitamin D2-A and CD ring fragment alcohols were synthesized by permanganate oxida-tion, selective bond cleavage and reduction from vitamin D2 . The total yield of D2-A and CD ring alco-hol were 30% and 45%, respectively. The structures were confirmed by 1 H NMR.