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Synthesis,Bioactivity and Crystal Structure Analysis of Novel Benzodisothiazol-3(2H)-ones

     

摘要

Two compounds,3-oxo-N-o-tolylbenzo[d]isothiazole-2(3H)-carboxamide (1) and N-(2-methoxyphenyl)-3-oxobenzo[d]isothiazole-2(3H)-carboxamide (2),were synthesized from the initial compound benzo[d]isothiazol-3(2H)-one (BIT) and characterized by 1 H NMR,IR and elemental analysis,respectively.The single crystals of compounds 1 and 2 were obtained and determined by X-ray diffraction analysis.The preliminary results of biological activity experiment show that some of the title compounds exhibited a favorable antimicrobial activity.

著录项

  • 来源
    《结构化学》|2012年第8期|1170-1174|共5页
  • 作者单位

    Institute of Environmental Science and Engineering,Kunming University of Science and Technology,Kunming 650093,China/Institute of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571100,China;

    Institute of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571100,China;

    Hainan Provincial Fine Chemical Engineering Center,Department of Materials and Chemical Engineering,Hainan University,Haikou 570228,China;

    Hainan Provincial Fine Chemical Engineering Center,Department of Materials and Chemical Engineering,Hainan University,Haikou 570228,China;

    Hainan Provincial Fine Chemical Engineering Center,Department of Materials and Chemical Engineering,Hainan University,Haikou 570228,China;

  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 镧系元素(稀土元素);
  • 关键词

    甲氧基苯基; 生物活性; 晶体结构分析; 噻唑; 合成; 标题化合物; X-射线衍射分析; 酮;

  • 入库时间 2023-07-25 12:41:29

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