三种常用侵入性产前诊断技术的临床结局分析

摘要

Objective we analyzed the success rate,effectiveness,safety and complications of these in-vasive diagnostic techniques.Method Summarized all invasive prenatal diagnostic surgical cases of Ab-dominal CVS,amniocentesis and umbilical vein puncture of Guangxi MCH genetic clinics from January 2010 to December 2012.Results Three kinds of invasive prenatal diagnostic techniques can safely and ef-fectively prevent birth defects,amniocentesis with the highest success rate,There is no significant differ-ence in the miscarriage rate.Conclusions Invasive prenatal diagnosis can safely and effectively prevent birth defects,and could be widely applied.%目的：了解3种侵入性产前诊断技术的成功率、有效性、安全性及其手术并发症。方法总结2010年1月至2012年12月广西壮族自治区妇幼保健院优生遗传门诊所进行的经腹绒毛穿刺、羊水穿刺、脐静脉穿刺手术病例，对其进行回顾性分析。结果3种侵入性产前诊断技术均能安全、有效地预防出生缺陷，羊水穿刺一次成功率最高，但流产率无显著性差异。结论侵入性产前诊断技术能安全有效地预防出生缺陷，值得推广。