一氧化碳中毒迟发性脑病患者预后相关因素分析

摘要

目的 分析一氧化碳中毒迟发性脑病患者预后的相关因素,为临床更好地判断一氧化碳中毒迟发性脑病预后提供依据.方法 一氧化碳中毒迟发性脑病患者52例,详细记录预后可能的相关因素,包括性别、年龄、昏迷时间、假愈期、一氧化碳中毒后是否行高压氧治疗,有无高血压、糖尿病病史,并在迟发性脑病高峰期进行生活自理能力评分及脑葡萄糖代谢测定.结果 影响一氧化碳中毒迟发性脑病患者临床预后的3个独立因素分别为性别、年龄和迟发性脑病假愈期时间(P＜0.05).结论 一氧化碳中毒迟发性脑病的预后与性别、年龄及假愈期时间有关,脑葡萄糖代谢值尚不能作为预测迟发性脑病预后的指标.%Objective To analyze related factors concerning prognosis in patients with delayed encephalopathy after carbon monoxide poisoning,and to provide clinical evidence for better assessment of prognosis of delayed encephalopathy after carbon monoxide poisoning.Methods Fifty-two cases of delayed encephalopathy after carbon monoxide poisoning were enrolled in our study.Such related factors as gender,age,duration of coma,false lucid interval time,HBO therapy,blood pressure and history of diabetes were all recorded in detail.Scores of activities of daily living (ADL) at the peak of delayed encephalopathy were recorded and cerebral glucose metabolism was monitored.Results The 3 independent factors affecting the clinical outcome of patients with delayed encephalopathy after carbon monoxide poisoning were gender,age and false lucid interval time (P ＜ 0.05).Conclusions The prognosis of delayed encephalopathy was associated with gender,age,and false lucid interval time,the value of cerebral glucose metabolism could not be used as an index for predicting the prognosis of delayed encephalopathy.