Objective To compare the therapeutic effects of video-assisted thoracoscopic lobectomy (VL) with traditional open surgery for lymphadenectomy in clinical stage Ⅰ non-small cell lung cancer.Methods From February 2008 to May 2009, 69 cases of clinical stage Ⅰ non-small cell lung cancer that were treated in our hospital were divided into VL ( n = 43 ) and open surgery ( n = 26) groups according to the patients' willingness.The total numbers of resected lymph nodes, lymph node groups, and positive lymph nodes, and the time of lymphadenectomy were recorded and compared between the two groups.Results There were no significant differences between the two groups in the total numbers of resected lymph nodes [( 12.1 ± 3.0 ) vs.( 13.1 ± 2.4 ), t = -1.442, P=0.154], N1 positive lymph nodes [(1.0±0.8) vs.(1.0 ±0.7), t =0.000, P=1.000]and N2 positive lymph nodes [(0.1 ± 0.2) vs.(0.1 ± 0.2 ), t = 0.000, P = 1.000].Whereas, VL group had significantly less resected lymph node groups [(4.2±0.7) vs.(4.7 ±0.9), t= -2.578, P=0.012], and longer time of lymphadenectomy [(33.8 ±8.7)min vs.(22.6± 3.9) min, t = 6.186, P = 0.000].Conclusions Lymphadenectomy in video-assisted thoracoscopic lobectomy shows the same effects as traditional open-surgery, but needs longer operation time.%目的 比较临床Ⅰ期非小细胞肺癌电视胸腔镜肺叶切除术(video-assisted thoracoscopic lobectomy,VL)与同期开胸手术中淋巴结清扫的效果.方法 选取我院2008年2月～2009年5月临床Ⅰ期非小细胞肺癌69例,按患者意愿非随机分为VL组(n=43)和开胸组(n=26).比较2组清扫淋巴结个数、清扫淋巴结组数、淋巴结转移阳性数和淋巴结清扫时间的差异.结果 2组淋巴结清扫数[(12.1±3.0)枚vs.(13.1±2.4)枚,t=-1.442,P=0.154],肺门(N1)阳性淋巴结数[(1.0±0.8)枚vs.(1.0±0.7)枚,t=0.000,P=1.000]和纵隔(N2)阳性淋巴结数[(0.1±0.2)枚vs.(0.1±0.2)枚,t=0.000,P=1.000]无显著性差异;但VL组淋巴结清扫组数少[(4.2±0.7)vs.(4.7±0.9),t=-2.578,P=0.012],清扫淋巴结时间长[(33.8±8.7)min vs.(22.6±3.9)min,t=6.186,P=0.000].结论 临床Ⅰ期非小细胞肺癌电视胸腔镜肺叶切除术中淋巴结清扫能达到开胸手术淋巴结清扫效果,但是手术时间相对较长.
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