三维超声造影在膀胱肿瘤分期中的应用价值

摘要

Objective To evaluate the effects of three-dimensional contrast-enhanced ultrasound ( 3D-CEUS ) in bladder tumor staging. Methods Sixty bladder tumor lesions from fifty-four patients examined by three-dimensional ultrasound ( 3D-US ), two-dimensional contrast-enhanced ultrasound ( 2D-CEUS ) and 3D-CEUS were analyzed retrospectively. The lesion boundary was indicated through post-treatment file after 3D image reconstruction, and compared with the pathologic stages. Results Sixty noninvasive tumors were revealed by pathology: 29 category Ta, 11 category T1 ;20 invasive tumors, including 4 category T2a, 6 category T2b , and 10 category > T2. The coincidence rate of 3D-CEUS with pathology in judging superficial tumors( Ta ), Lamina propria infiltrating tumors ( T1 ), invasive tumors ( > T1 ) were 72. 4% ( 21/29 ), 90.9%( 10/11 ) and 100%( 20/20 ),respectively. The overall accuracy was 85.0%( 51/60 ). Conclusion 3D-CEUS can estimate the invasion depth of bladder tumor accurately and improve the diagnostic accuracy of bladder tumor staging before operation.%目的 探讨三维超声造影(3D-CEUS)在膀胱肿瘤分期中的应用价值.方法 回顾性分析54例膀胱肿瘤患者共60个膀胱肿瘤三维超声检查、二维超声造影和3D-CEUS图像资料,重建三维超声造影图像后利用后处理软件观察病灶的边界,并与病理结果进行比较.结果 60个膀胱肿瘤经手术后病理证实表浅型膀胱肿瘤(Ta期)29个,侵犯皮下结缔组织的肿瘤(T1期)11个,浸润性膀胱肿瘤(＞T1期)20个(分别为T2a期4个,T2b期6个,＞T2期10个).膀胱肿瘤3D-CEUS术前分期与病理结果的符合率分别为:Ta期72.4%(21/29),T1期90.9%(10/11),＞T1期100%(20/20),总符合率为 85.0%(51/60).结论 3D-CEUS 可以较准确地判断膀胱肿瘤浸润膀胱壁的深度,可提高膀胱肿瘤术前分期诊断准确率.