原子力显微镜在生命科学研究中的应用

摘要

The atomic force microscope (AFM), an indispensable tool on the field of scientific research of life, has been uesd to study the biomacromolecule rescently. The new progress on hyaluronic acid (HA) and tubular myelin (TM) through the tool vas obvious. Thestudy on super-elementary units of chromatin in the nanometer (nm) scale is a base step for the higher level. AFM provided the possibility of killing viras in physical method, with studying on the effect of the mechanical resonances on living cells. As far as the medicine concerned, basic condition of test in clinic pathodogy has been formed in some fields.%原子力显微镜(AFM)是生命科学研究中不可缺少的工具。用它研究生物大分子，最近在"透明质酸"，"髓鞘质"研究中有了新的进展；在纳米水平研究染色质的超级结构，为下一级结构的研究打开了缺口；用它研究活细胞的力学响应，为用物理方法制服病毒提供了可能性；就医学研究而言，在某些领域内已初步具备了进入临床病理学检验的基本条件。