比较不同感染途径HIV感染者合并HBV、HCV感染的情况

摘要

目的 比较不同感染途径HIV感染者合并感染HBV和/或HCV感染率差异.方法 对626例HIV感染者进行HBV、HCV病毒血清学标记物的检查.观察对象中经血液途径感染HIV者为395例.经性传播途径感染HIV者为231例.结果 395例经血液传播的HIV感染者HBsAg阳性者占5.06％(20/395)、HCV感染者占66.3％(262/395).经血液途径感染的HIV感染者合并HBV感染率明显低于合并HCV感染率,差异有统计学意义(x2=323,P＜0.05).231例经性传播途径感染HIV感染者合并HBV感染率(HBsAg阳性)为12.55％(29/231)、合并HCV感染率为6.49％(15/231),经性传播途径感染的HIV感染者合并HBV感染率明显高于合并HCV感染率,差异有统计学意义(x2 =4.923,P＜0.05).经性传播途径及血液途径感染的HIV感染者合并HBV(HBsAg阳性)感染率分别为12.55％(29/231)、5.06％(20/395),前者高于后者,且差异有统计学意义(x2=11.34,P＜0.01).经性传播途径和血液途径感染的HIV/AIDS感染者合并HCV感染率分别为6.49％ (15/231)、66.3％(262/395),经血液途径感染的HIV感染者合并HCV感染率明显高于经性传播途径感染者,且差异有统计学意义(x2=211.50,P＜0.01).结论 经性接触途径感染HIV感染者,其合并HBV感染率高于合并HCV感染率.然而,经血液途径感染的HIV感染者,其合并HBV感染率低于合并HCV感染率.%Objective Comparison of the infection prevalence of HBV、HCV in HIV/AIDS infectors transmitted by the different infection routes.Methods HBV and HCV serological markers were detected in 626 HIV/AIDS infectors from inpatient or outpatient.Among 626 patients,395 cases were infected HIV by blood route and the left were infected by sex contact route.Results The HBV prevalence was 5.06％ and the HCV prevalence was 66.3％ in HIV/AIDS patients via blood infection route,and the difference is significant (x2 =323,P＜0.05).The HBV prevalence was 12.55 ％ and the HCV prevalence was 6.49 ％ in HIV/AIDS patients via sex contact infection route.The former is higher than the latter,but the difference is insignificant.The HBV prevalence of HIV/AIDS patients via sex contact route and blood infection route was 12.55％,5.06％,respectively,and the difference is significant.However,the HBV prevalence of HIV/AIDS patients via sex contact route and blood infection route was 6.49％,66.3％,respectively,and the difference is significant (x2=211.50,P＜0.01).Conclusion The HBV prevalence was significant higher in HIV/AIDS patients via sex contact route than those via blood route.The HCV prevalence was significant lower in HIV/AIDS patients via sex contact route than those via blood route.