炎症性肠病(IBD)主要包括溃疡性结肠炎(UC)和克罗恩病(CD),近年其发病呈上升趋势.IBD的发病机制尚不明确,研究表明免疫炎症反应起重要作用.白细胞介素33(IL-33)是新近发现的炎症因子,越来越多证据表明其参与IBD发病.本文就IL-33在IBD炎症进展和黏膜愈合中的作用作一综述.%Inflammatory bowel disease (IBD) consists of ulcerative colitis ( UC ) and Crohn ' s disease ( CD) . The incidence of IBD has increased in recent years, but the etiology is still unclear. Many studies have proved that immune inflammatory response plays a critical role in the development of IBD. Interleukin 33 (IL-33 ) is a recently discovered inflammatory factor, more and more studies suggest it contributes to the development of IBD. This article reviewed the role of IL-33 in inflammation progress and mucosal healing of IBD.
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