心尖肥厚型心肌病窦性心率震荡与预后

摘要

Objective To study the values of diminished or disappeared heart rate turbulence ( HRT ) in the long-term prognosis of apical hypertrophic cardiomyopathy ( AHCM ). Methods According to the occurrence of ventricular arrhythmias, heart failure, acute myocardial infarction and cardiac death,68 AHCM patients were divided into the cardiovascular event group and control group. The information of electrocardiogram was recorded in two groups by using dynamic electrocardiogram technology and the difference in the indexes of HRT between two groups was compared and analysed. Results The turbulence onset ( TO ) in two groups was, respectively,( 0.24 ± 1.55 ) ％ and ( - 0.21 ± 1.89 ) ％, and the difference was significant statistically ( P ＜ 0.05 ). The turbulence slope ( TS ) in two groups was,respectively ,( 2.83 ± 0.58 ) ms/RR and ( 11.07 ± 4.39 ) ms/RR, and the difference was greatly significant statistically ( P ＜ 0.01 ). Conclusion HRT will be diminished or disappear in the patient with AHCM and cardiovascular events.The indexes of HRT can be a help in the prognosis of AHCM.%目的 探讨窦性心率震荡的减弱或消失对心尖肥厚型心肌病远期预后的价值.方法 根据有无室性心律失常、心力衰竭、急性心肌梗死和心源性死亡的发生,将68例心尖肥厚型心肌病患者分为心血管事件组和对照组.并应用动态心电图技术记录两组的心电信息,对比分析两组患者心率震荡指标的差异.结果 心血管事件组和对照组心率震荡起始分别为(0.24±1.55)%和(-0.21±1.89)%,差异有统计学意义(P＜0.05);震荡斜率分别为(2.83±0.58) ms/RR和(11.07±4.39) ms/RR,差异有显著统计学意义(P＜0.01).结论 心尖肥厚型心肌病发生心血管事件的患者窦性心率震荡明显减弱或消失,窦性心率震荡的指标可以为心尖肥厚型心肌病的预后提供帮助.