Over recent 30 years,fMRI has emerged as one of the most popular brain imaging techniques with highly spatiotemporal resolution and noninvasiveness,and has promoted the development of brain science.However,it still faces numerous challenges in the application of clinical translation.Based on the principles,technical research and development,and clinical applications,this review will discuss existing problems and future directions of fMRI.%fMRI问世近30年来,以适宜的高时间和空间分辨力及无创性优点,成为最热门的脑成像技术,推动脑科学发展.然而,其在临床诊断转化应用方面尚有诸多挑战.本文拟从fMRI原理、技术研发和临床诊断转化应用特点方面,分析其存在问题、展望其发展方向.
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