PHARMACEUTICAL COMBINATION INFLUENCING CENTRAL NERVOUS SYSTEM FUNCTION; METHOD OF CORRECTING CONDITIONS ASSOCIATED WITH DYSFUNCTION OF CENTRAL NERVOUS SYSTEM; PHARMACEUTICAL KIT; AGENT ASSISTING THERAPEUTICAL SUBSTANCES AND METABOLITES TO CROSS BLOOD-BRAIN BARRIER; AND ENDONASAL DRUG

摘要

FIELD: pharmacology.;SUBSTANCE: invention provides a pharmaceutical combination influencing central nervous system function, which contains (i) at least one compound influencing central nervous system function; (ii) at least one compound beneficially affecting central nervous system, and compound assisting first compound to cross blood-brain barrier, namely an agent for endonasal administration manifesting reflex, preferably neuro- and vasoactive action on nasal mucosa structures and receptors, basically receptors of vomeronasal organ and trigeminal nerve systems; (iii) active oxygen forms selected from hydrogen superoxide, hydrogen peroxide, NO^-, and CO-active compounds; and (iv) pharmacological stabilizer.;EFFECT: lowered doses and reduced adverse effects.;22 cl, 2 tbl, 8 ex