五味子中提取α-葡萄糖苷酶抑制剂的研究

摘要

目的从中药五味子中提取分离α-葡萄糖苷酶抑制剂。方法利用浸提、超滤、柱层析、醋酸铅沉淀等方法进行纯化。结果初步分离得到α-葡萄糖苷酶抑制剂。结论该抑制剂成分为大分子糖苷类物质，相对分子量在5万以上，抑制类型为非竞争性抑制。%Purpose　The aim is to study α-glucosidase inhibitor from Schisandra Chinensis(Turcz.)Baill.Methods　The inhibitor was purified by soaking,ultrafiltration,ion-exchange chromatography and Lead Acetate deposition.Results　A α-glucosidase inhibitor was obtained.Conclusion　The inhibitor was a kind of non-competition inhibitor with large molecular weight of over 5×105D.