心理干预联合比索洛尔、曲美他嗪治疗左心室射血分数保留的心力衰竭的临床研究

摘要

Objective To study the clinical effect of psychological intervention combined with trimetazidine and bisoprolol in the treatment of left ventricular ejection fraction with heart failure. Methods 40 patients with heart failure were enrolled in this study. 40 patients were divided into control group and study group by digital randomization. There were 20 patients in each group and the patients in the control group.The patients were treated with trimetazidine and bisoprolol. The study group was treated with psychological intervention on the basis of the treatment. The clinical efficacy, adverse reactions, left ventricular ejection fraction and anxiety self-rating were analyzed (SAS), self-rating depression scale (SDS) score. Results The total effective rate of the clinical treatment group was 90.00％ higher than that of the control group (70.00％)P<0.05. There was no significant difference between the two groups in the adverse reaction. The mean left ventricular ejection fraction of the study group was (40.25 ± 5.24), which was significantly lower than that of the control group (43.92 ± 5.30). The scores of the study group were (50.26 ± 1.35) and (51.38 ± 2.61) respectively in SAS and SDS scores (54.36 ± 2.60), (56.98 ± 3.25) in the control group, (P<0.05). Conclusion The patients with left ventricular ejection fraction retention psychological failure in the application of trimetazidine, bisoprolol treatment based on the necessary psychological intervention, can effectively improve the patient's negative emotions, improve patient compliance, and then improve clinical efficacy, clinical significant application value.%目的 研究心理干预联合曲美他嗪、比索洛尔在左心室射血分数保留心力衰竭中治疗的临床效果.方法 选取在本院进行住院治疗的左心室射血分数保留心力衰竭患者40例作为研究对象,应用数字随机法将患者分为对照组与研究组,每组各有20例患者,对照组的患者应用曲美他嗪与比索洛尔进行治疗,研究组在该治疗基础上对患者进行针对性的心理干预,对比分析2组患者临床疗效、不良反应情况、左室射血分数和焦虑自评量表(SAS)、抑郁自评量表(SDS)得分情况.结果 研究组临床治疗总有效率为90.00％明显高于对照组的70.00％(P<0.05);2组不良反应发生率比较差异无统计学意义;研究组左室射血分数平均为(40.25±5.24)明显低于对照组(43.92±5.30),研究组SAS、SDS评分分别为(50.26±1.35)、(51.38±2.61),显著优于对照组的(54.36±2.60)、(56.98±3.25),差异均具有统计学意义(P<0.05).结论 对左心室射血分数保留心理衰竭患者在应用曲美他嗪、比索洛尔治疗的基础上进行必要的心理干预,能有效改善患者不良情绪,提高患者治疗依从性,进而提高临床疗效,临床应用价值显著.