Rest and Exercise Left Ventricular Ejection Fraction Before and After Therapy in Young Adults with Hyperthyroidism and Hypothyroidism

摘要

Thyroid hormone has numerous direct and indirect effects on cardiac function, and alterations in thyroid status may complicate preexisting cardiac disease. Ikram showed that cardiac failure may develop in thyrotoxic patients. Although clinical evidence of underlying cardiac disease was excluded, the mean age of his patients was 60 years. Several recent studies suggest that in middle-aged or older hyperthyroid or hypothyroid persons, cardiac reserve (determined by exercise radionuclide angiography) is impaired in the absence of underlying heart disease. The present study was performed to determine whether younger adult patients also had evidence of a thyroid cardiomyopathy. Reprints. (mjm/aw)